CDC37L1 Література | Примітки | Див. також | Навігаційне менюPDBeRCSB1US72K5B2W0GCDC37L119143229912CDC37L1unfolded protein bindingchaperone bindingprotein bindingheat shock protein bindingplatelet dense granule lumenextracellular regionЦитоплазмаГіалоплазмаprotein stabilizationЗгортання білківplatelet degranulationAmigoQuickGO5566467072ENSG00000106993ENSMUSG00000024780Q7L3B6Q9CZP7NM_017913NM_025950NM_001302380NM_001302382NM_001302443NP_060383NP_001289309NP_001289311NP_001289372NP_080226Хр. 9: 4.68 – 4.71 MbХр. 19: 28.99 – 29.03 MbPubMed10.1101/gr.2596504PubMed10.1074/jbc.M103889200PubMed10.1021/bi047406zPubMed10.1021/bi701041pHuman PubMed Reference:Mouse PubMed Reference:HUGO Gene Nomenclature Commitee, HGNC:17179UniProt, Q7L3B6виправивши або дописавши їїпідказкою

Гени на хромосомі 9Некатегоризовані білки


англ.амінокислотмолекулярна масашаперонівфосфопротеїнівцитоплазмі


































CDC37L1




Наявні структури
PDBПошук ортологів: PDBe RCSB

Ідентифікатори

Символи

CDC37L1, CDC37B, HARC, cell division cycle 37 like 1
Зовнішні ІД
MGI: 1914322 HomoloGene: 9912 GeneCards: CDC37L1








Ортологи
ВидиЛюдинаМиша
Entrez

55664


67072
Ensembl

ENSG00000106993


ENSMUSG00000024780
UniProt

Q7L3B6


Q9CZP7
RefSeq (мРНК)

NM_017913


NM_025950
NM_001302380
NM_001302382
NM_001302443
RefSeq (білок)

NP_060383

NP_001289309
NP_001289311
NP_001289372
NP_080226
Локус (UCSC)
Хр. 9: 4.68 – 4.71 Mb

Хр. 19: 28.99 – 29.03 Mb

PubMed search
[1]
[2]
Вікідані


Див./Ред. для людейДив./Ред. для мишей

CDC37L1 (англ. Cell division cycle 37 like 1) – білок, який кодується однойменним геном, розташованим у людей на 9-ї хромосомі.[3] Довжина поліпептидного ланцюга білка становить 337 амінокислот, а молекулярна маса — 38 835[4].



Послідовність амінокислот








































































1020304050

MEQPWPPPGP

WSLPRAEGEA

EEESDFDVFP

SSPRCPQLPG

GGAQMYSHGI

ELACQKQKEF

VKSSVACKWN

LAEAQQKLGS

LALHNSESLD

QEHAKAQTAV

SELRQREEEW

RQKEEALVQR

EKMCLWSTDA

ISKDVFNKSF

INQDKRKDTE

DEDKSESFMQ

KYEQKIRHFG

MLSRWDDSQR

FLSDHPYLVC

EETAKYLILW

CFHLEAEKKG

ALMEQIAHQA

VVMQFIMEMA

KNCNVDPRGC

FRLFFQKAKA

EEEGYFEAFK

NELEAFKSRV

RLYSQSQSFQ

PMTVQNHVPH

SGVGSIGLLE

SLPQNPDYLQ

YSISTALCSL

NSVVHKEDDE

PKMMDTV


Кодований геном білок за функціями належить до шаперонів, фосфопротеїнів.
Локалізований у цитоплазмі.



Література |


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  • The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).. Genome Res. 14: 2121 — 2127. 2004.  PubMed DOI:10.1101/gr.2596504


  • Scholz G.M., Cartledge K., Hall N.E. (2001). Identification and characterization of Harc, a novel Hsp90-associating relative of Cdc37.. J. Biol. Chem. 276: 30971 — 30979.  PubMed DOI:10.1074/jbc.M103889200


  • Roiniotis J., Masendycz P., Ho S., Scholz G.M. (2005). Domain-mediated dimerization of the Hsp90 cochaperones Harc and Cdc37.. Biochemistry 44: 6662 — 6669.  PubMed DOI:10.1021/bi047406z


  • Cartledge K., Elsegood C., Roiniotis J., Hamilton J.A., Scholz G.M. (2007). Importance of the C-terminal domain of harc for binding to hsp70 and hop as well as its response to heat shock.. Biochemistry 46: 15144 — 15152.  PubMed DOI:10.1021/bi701041p



Примітки |




  1. ↑ Human PubMed Reference:. 


  2. ↑ Mouse PubMed Reference:. 


  3. ↑ HUGO Gene Nomenclature Commitee, HGNC:17179 (англ.). Процитовано 19 вересня 2017. 


  4. ↑ UniProt, Q7L3B6 (англ.). Процитовано 19 вересня 2017. 



Див. також |


  • Хромосома 9



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