PDCD10 Література | Примітки | Див. також | Навігаційне менюPDBeRCSB3AJM3L8I3L8J3RQE3RQF3RQG3W8H3W8I4GEH4TVQPDCD10192839610505PDCD10protein homodimerization activityprotein N-terminus bindingprotein bindingprotein kinase bindingЦитоплазмаГіалоплазмаКомплекс ҐольджімембранаGolgi membraneЦитоплазматична мембранаextracellular exosomeintrinsic apoptotic signaling pathway in response to hydrogen peroxidepositive regulation of MAP kinase activitypositive regulation of cell migrationprotein stabilizationnegative regulation of apoptotic processnegative regulation of gene expressionestablishment of Golgi localizationstress fiber assemblypositive regulation of peptidyl-serine phosphorylationpositive regulation of protein serine/threonine kinase activityGolgi reassemblynegative regulation of cell migration involved in sprouting angiogenesispositive regulation of gene expressionАнгіогенезpositive regulation of cell proliferationnegative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesisregulation of Rho protein signal transductionresponse to hydrogen peroxidewound healing, spreading of cellspositive regulation of Notch signaling pathwaypositive regulation of stress-activated MAPK cascadeАпоптозpositive regulation of intracellular protein transportcellular response to leukemia inhibitory factorAmigoQuickGOБільше даних1123556426ENSG00000114209ENSMUSG00000027835Q9BUL8Q8VE70NM_007217NM_145859NM_145860NM_019745NP_009148NP_665858NP_665859NP_062719Хр. 3: 167.68 – 167.73 MbХр. 3: 75.52 – 75.56 MbPubMed10.1101/gr.2596504PubMed10.1242/jcs.198614Human PubMed Reference:Mouse PubMed Reference:HUGO Gene Nomenclature Commitee, HGNC:8761UniProt, Q9BUL8виправивши або дописавши її

Гени на хромосомі 3Некатегоризовані білки


англ.амінокислотмолекулярна масаапоптозангіогенезклітинній мембраніцитоплазміапараті гольджі




































PDCD10
Protein PDCD10 PDB 3AJM.png




Наявні структури
PDBПошук ортологів: PDBe RCSB

Ідентифікатори

Символи

PDCD10, CCM3, TFAR15, programmed cell death 10
Зовнішні ІД
MGI: 1928396 HomoloGene: 10505 GeneCards: PDCD10








Шаблон експресії
PBB GE PDCD10 210907 s at fs.png

Більше даних
Ортологи
ВидиЛюдинаМиша
Entrez

11235


56426
Ensembl

ENSG00000114209


ENSMUSG00000027835
UniProt

Q9BUL8


Q8VE70
RefSeq (мРНК)

NM_007217
NM_145859
NM_145860


NM_019745
RefSeq (білок)

NP_009148
NP_665858
NP_665859

NP_062719
Локус (UCSC)
Хр. 3: 167.68 – 167.73 Mb

Хр. 3: 75.52 – 75.56 Mb

PubMed search
[1]
[2]
Вікідані


Див./Ред. для людейДив./Ред. для мишей

PDCD10 (англ. Programmed cell death 10) – білок, який кодується однойменним геном, розташованим у людей на короткому плечі 3-ї хромосоми. [3] Довжина поліпептидного ланцюга білка становить 212 амінокислот, а молекулярна маса — 24 702[4].



Послідовність амінокислот


















































1020304050

MRMTMEEMKN

EAETTSMVSM

PLYAVMYPVF

NELERVNLSA

AQTLRAAFIK

AEKENPGLTQ

DIIMKILEKK

SVEVNFTESL

LRMAADDVEE

YMIERPEPEF

QDLNEKARAL

KQILSKIPDE

INDRVRFLQT

IKDIASAIKE

LLDTVNNVFK

KYQYQNRRAL

EHQKKEFVKY

SKSFSDTLKT

YFKDGKAINV

FVSANRLIHQ

TNLILQTFKT

VA


Задіяний у таких біологічних процесах як апоптоз, ангіогенез, поліморфізм, ацетиляція.
Локалізований у клітинній мембрані, цитоплазмі, мембрані, апараті гольджі.



Література |


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  • The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).. Genome Res. 14: 2121 — 2127. 2004.  PubMed DOI:10.1101/gr.2596504


  • Mardakheh F.K., Self A., Marshall C.J. (2016). RHO binding to FAM65A regulates Golgi reorientation during cell migration.. J. Cell Sci. 129: 4466 — 4479.  PubMed DOI:10.1242/jcs.198614


  • Wang Y.G., Liu H.T., Ma D.L., Zhang Y.M. (1999). cDNA cloning and expression of an apoptosis-related gene, human TFAR-15 gene.. Sci. China, Ser. C, Life Sci. 42: 323 — 329. 



Примітки |




  1. ↑ Human PubMed Reference:. 


  2. ↑ Mouse PubMed Reference:. 


  3. ↑ HUGO Gene Nomenclature Commitee, HGNC:8761 (англ.). Процитовано 30 серпня 2017. 


  4. ↑ UniProt, Q9BUL8 (англ.). Процитовано 30 серпня 2017. 



Див. також |


  • Хромосома 3



Молекула міоглобіну
Це незавершена стаття про білки.
Ви можете допомогти проекту, виправивши або дописавши її.

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